Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-11-10
pubmed:databankReference
pubmed:abstractText
Cloning and sequencing of the circular, single-stranded DNA of one isolate of psittacine beak and feather disease virus (BFDV) demonstrate a genome composed of a circular molecule of 1993 nucleotide bases. An analysis of the assembled replicative form demonstrated seven open reading frames (ORFs) (three in the virion strand and four in the complementary strand), potentially encoding seven viral proteins of >8.7 kDa. High amino acid sequence similarity was demonstrated between a potential 33.3-kDa protein product of ORF1 of BFDV and the replicase-associated protein of porcine circovirus (PCV), subterranean clover stunt virus, and faba bean necrotic yellows virus. However, significant similarity in nucleotide or amino acid sequences was not present between BFDV and chicken anaemia virus. A potential stem-loop structure similar to that found in PCV and plant circoviruses was present in the putative encapsidated strand of the BFDV genome. At the top of this structure, a nonanucleotide motif (TAGTATTAC) similar to that of PCV, plant circoviruses, and geminiviruses also was recognised. Comparison of the deduced amino acid sequences of ORF2 of BFDV and PCV demonstrated 29.1% identity, and in both viruses, ORF2 is located on the complementary strand, beginning close to or within the hairpin stem. Our findings provide further evidence of a close relationship among BFDV, PCV, and plant circoviruses but not chicken anaemia virus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0042-6822
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press.
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
249
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
453-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9791035-Amino Acid Sequence, pubmed-meshheading:9791035-Animals, pubmed-meshheading:9791035-Base Sequence, pubmed-meshheading:9791035-Chicken anemia virus, pubmed-meshheading:9791035-Chickens, pubmed-meshheading:9791035-Circovirus, pubmed-meshheading:9791035-Cloning, Molecular, pubmed-meshheading:9791035-DNA, Viral, pubmed-meshheading:9791035-DNA Primers, pubmed-meshheading:9791035-Genome, Viral, pubmed-meshheading:9791035-Molecular Sequence Data, pubmed-meshheading:9791035-Nucleic Acid Conformation, pubmed-meshheading:9791035-Open Reading Frames, pubmed-meshheading:9791035-Plant Viruses, pubmed-meshheading:9791035-Polymerase Chain Reaction, pubmed-meshheading:9791035-Psittaciformes, pubmed-meshheading:9791035-Sequence Homology, Amino Acid, pubmed-meshheading:9791035-Species Specificity, pubmed-meshheading:9791035-Swine
pubmed:year
1998
pubmed:articleTitle
Psittacine beak and feather disease virus nucleotide sequence analysis and its relationship to porcine circovirus, plant circoviruses, and chicken anaemia virus.
pubmed:affiliation
Division of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, 6150, Western Australia.
pubmed:publicationType
Journal Article, Comparative Study