| pubmed-article:9780247 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0019682 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C1332717 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C1706438 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0032105 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0085358 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0035668 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0007586 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C1413244 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C2698600 | lld:lifeskim |
| pubmed-article:9780247 | lifeskim:mentions | umls-concept:C1879547 | lld:lifeskim |
| pubmed-article:9780247 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:9780247 | pubmed:dateCreated | 1998-12-10 | lld:pubmed |
| pubmed-article:9780247 | pubmed:abstractText | The relationship between T cell activation and human immunodeficiency virus type 1 (HIV-1) replication was studied in HIV-infected subjects, 20 with and 10 without anti-HIV treatment. Expression of Ki-67 proliferation-associated antigen was increased in CD4+ and CD8+ T cells and correlated with HLA-DR. In subjects without anti-HIV treatment, the plasma HIV-1 RNA level correlated with HLA-DR in CD4+ T cells, with Ki-67 in CD8+ T cells, and with expression of CD38 in both T cell subsets. A proportion of treated subjects had increased T cell activation despite 4 months of highly active antiretroviral treatment (HAART). In subjects receiving HAART, a high percentage of HLA-DR+ CD4+ T cells was associated with signs of opportunistic infections. This work supports the concept that, in the natural course of HIV-1 infection, HIV replication itself leads to general T cell activation and that opportunistic infections generate additional CD4+ T cell activation and HIV replication. | lld:pubmed |
| pubmed-article:9780247 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9780247 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9780247 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9780247 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:9780247 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:VerhoefJJ | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:de VosN MNM | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:SnippeHH | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:BoucherC ACA | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:VisserM RMR | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:BorleffsJ CJC | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:BloemA CAC | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:NottetH SHS | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:OrendiJ MJM | lld:pubmed |
| pubmed-article:9780247 | pubmed:author | pubmed-author:WijnholdsF... | lld:pubmed |
| pubmed-article:9780247 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9780247 | pubmed:volume | 178 | lld:pubmed |
| pubmed-article:9780247 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9780247 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9780247 | pubmed:pagination | 1279-87 | lld:pubmed |
| pubmed-article:9780247 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:meshHeading | pubmed-meshheading:9780247-... | lld:pubmed |
| pubmed-article:9780247 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9780247 | pubmed:articleTitle | Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection. | lld:pubmed |
| pubmed-article:9780247 | pubmed:affiliation | Department of Medical Microbiology, Leiden University Medical Center, The Netherlands. | lld:pubmed |
| pubmed-article:9780247 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9780247 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9780247 | lld:pubmed |
