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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1999-6-7
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pubmed:abstractText |
We measured the concentrations of the neuron-specific protein, tau, in the cerebrospinal fluid (CSF) of 32 neurologically characterized HIV-infected (HIVpos) subjects and nine matched seronegative (HIVneg) controls using a sensitive ELISA assay. Of 32 HIVpos subjects, nine had HIV-associated neurocognitive disorders, and nine had clinically diagnosed peripheral neuropathies. CSF tau levels in subjects with HIV-associated neurocognitive disorders were similar to those in HIVneg subjects (185 +/- 83 vs. 223 +/- 106 pg/ml; P = 57). CSF tau levels in HIVpos subjects with peripheral neuropathies did not differ from those without neuropathies (320 +/- 190 vs. 251 +/- 185; P = 23). In summary, CSF tau levels were not elevated in patients with HIV-associated neurologic disease.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
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pubmed:issn |
0304-3940
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
18
|
pubmed:volume |
254
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1-4
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9780077-AIDS Dementia Complex,
pubmed-meshheading:9780077-Adult,
pubmed-meshheading:9780077-Cohort Studies,
pubmed-meshheading:9780077-Female,
pubmed-meshheading:9780077-HIV Infections,
pubmed-meshheading:9780077-Humans,
pubmed-meshheading:9780077-Longitudinal Studies,
pubmed-meshheading:9780077-Male,
pubmed-meshheading:9780077-Middle Aged,
pubmed-meshheading:9780077-Peripheral Nervous System Diseases,
pubmed-meshheading:9780077-Prospective Studies,
pubmed-meshheading:9780077-tau Proteins
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pubmed:year |
1998
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pubmed:articleTitle |
Cerebrospinal fluid tau protein is not elevated in HIV-associated neurologic disease in humans. HIV Neurobehavioral Research Center Group (HNRC).
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pubmed:affiliation |
Department of Neurosciences, University of California, San Diego, USA. roellis@ucsd.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|