| pubmed-article:9770349 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0021756 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0016057 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0079349 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:9770349 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:9770349 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:9770349 | pubmed:dateCreated | 1998-11-13 | lld:pubmed |
| pubmed-article:9770349 | pubmed:abstractText | FGF-1 stimulated DNA synthesis and induced expression of IL-2 receptors in the murine fibrosarcoma cell line, F69-3. Concomitant treatment with IL-2 abolished the stimulation of DNA synthesis, but not binding of FGF-1 to the FGF-receptors or subsequent endocytosis of the bound growth factor. Also, it did not inhibit activation of the FGF-receptor tyrosine kinase or stimulation of the downstream effector, MAP kinase. Treatment with IL-2 prevented transport of FGF-1 to the nuclear fraction in a time- and dose-dependent manner that parallelled the inhibition of FGF-1 stimulated DNA synthesis. The data support our earlier finding that transport of FGF-1 to the nucleus is an important event in the mechanism of stimulation of DNA synthesis induced by the growth factor, and they demonstrate that treatment with a cytokine can modulate the cellular response to FGF-1. | lld:pubmed |
| pubmed-article:9770349 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9770349 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9770349 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9770349 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9770349 | pubmed:issn | 0014-4827 | lld:pubmed |
| pubmed-article:9770349 | pubmed:author | pubmed-author:OlsnesSS | lld:pubmed |
| pubmed-article:9770349 | pubmed:author | pubmed-author:RadzikowskiCC | lld:pubmed |
| pubmed-article:9770349 | pubmed:author | pubmed-author:Wied?ochaAA | lld:pubmed |
| pubmed-article:9770349 | pubmed:author | pubmed-author:ZaleckiPP | lld:pubmed |
| pubmed-article:9770349 | pubmed:copyrightInfo | Copyright 1998 Academic Press. | lld:pubmed |
| pubmed-article:9770349 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9770349 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:9770349 | pubmed:volume | 244 | lld:pubmed |
| pubmed-article:9770349 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9770349 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9770349 | pubmed:pagination | 61-70 | lld:pubmed |
| pubmed-article:9770349 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:9770349 | pubmed:meshHeading | pubmed-meshheading:9770349-... | lld:pubmed |
| pubmed-article:9770349 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9770349 | pubmed:articleTitle | Modulation by interleukin-2 of cellular response to fibroblast growth factor-1 in F69-3 fibrosarcoma cells. | lld:pubmed |
| pubmed-article:9770349 | pubmed:affiliation | Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, 0310 Oslo, Norway. | lld:pubmed |
| pubmed-article:9770349 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9770349 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9770349 | lld:pubmed |
