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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1998-11-16
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pubmed:abstractText |
A 45-year-old man with a glucagonoma and necrolytic migratory erythema is described. Clinical, radiographic, and histologic features were typical for this syndrome. However, a skin biopsy specimen for direct immunofluorescence examination revealed apoptotic keratinocytes that stained positive with immunoglobulins, fibrinogen, and C3. These immunofluorescence findings were initially interpreted erroneously as showing erythema multiforme or a related disorder. We present a unique case of necrolytic migratory erythema with positive direct immunofluorescence findings reflecting immunoglobulin and complement deposition within dyskeratotic epithelial cells.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0011-4162
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
62
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
129-32
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:9770127-Apoptosis,
pubmed-meshheading:9770127-Complement C3,
pubmed-meshheading:9770127-Erythema,
pubmed-meshheading:9770127-Fibrinogen,
pubmed-meshheading:9770127-Fluorescent Antibody Technique, Direct,
pubmed-meshheading:9770127-Glucagonoma,
pubmed-meshheading:9770127-Humans,
pubmed-meshheading:9770127-Immunoglobulin G,
pubmed-meshheading:9770127-Immunoglobulin M,
pubmed-meshheading:9770127-Keratinocytes,
pubmed-meshheading:9770127-Male,
pubmed-meshheading:9770127-Middle Aged,
pubmed-meshheading:9770127-Necrosis,
pubmed-meshheading:9770127-Pancreatic Neoplasms,
pubmed-meshheading:9770127-Skin,
pubmed-meshheading:9770127-Tomography, X-Ray Computed
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pubmed:year |
1998
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pubmed:articleTitle |
Apoptosis with positive direct immunofluorescence findings in a patient with necrolytic migratory erythema.
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pubmed:affiliation |
Department of Dermatology, Mayo Clinic Jacksonville, Florida 32224, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
|