| pubmed-article:9765450 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0019704 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C1332717 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C1706438 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0024264 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0085358 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C1413244 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C2698600 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9765450 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9765450 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:9765450 | pubmed:dateCreated | 1998-11-5 | lld:pubmed |
| pubmed-article:9765450 | pubmed:abstractText | Human immunodeficiency virus type 1 (HIV-1) infection requires cell surface expression of CD4. Costimulation of CD8(+)/CD4(-) T lymphocytes by anti-CD3 and anti-CD28 antibodies or by allogeneic dendritic cells induced expression of CD4 and rendered these CD8 cells susceptible to HIV-1 infection. Naive CD45RA+ cells responded with greater expression of CD4 than did CD45RO+ cells. CD8(+) lymphocytes derived from fetal or newborn sources exhibited a greater tendency to express CD4, consistent with their naive states. This mechanism of infection suggests HIV-induced perturbation of the CD8 arm of the immune response and could explain the generally rapid disease progression seen in HIV-infected children. | lld:pubmed |
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| pubmed-article:9765450 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9765450 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9765450 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9765450 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9765450 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9765450 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:9765450 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:9765450 | pubmed:author | pubmed-author:RothM DMD | lld:pubmed |
| pubmed-article:9765450 | pubmed:author | pubmed-author:LandayAA | lld:pubmed |
| pubmed-article:9765450 | pubmed:author | pubmed-author:ZackJ AJA | lld:pubmed |
| pubmed-article:9765450 | pubmed:author | pubmed-author:KitchenS GSG | lld:pubmed |
| pubmed-article:9765450 | pubmed:author | pubmed-author:KorinY DYD | lld:pubmed |
| pubmed-article:9765450 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9765450 | pubmed:volume | 72 | lld:pubmed |
| pubmed-article:9765450 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9765450 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9765450 | pubmed:pagination | 9054-60 | lld:pubmed |
| pubmed-article:9765450 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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