Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-12-21
pubmed:abstractText
The pathogenesis of sarcoidosis has intrigued clinicians since the first descriptions of the disease, and a number of causes have been proposed. Among the candidate agents, the possible role of mycobacterial infection in the pathogenesis of sarcoidosis has attracted by far the most attention. The purpose of this review is to summarize current evidence concerning the role of mycobacterial infection in sarcoidosis. First, the similarities in clinical and histological features of tuberculosis and sarcoidosis that have raised suspicion that mycobacterial infection could be involved in the pathogenesis of sarcoidosis are discussed. In addition, experimental evidence for and against a role of mycobacterial infection is summarized, including recent attempts to detect mycobacterial DNA in clinical samples from patients with sarcoidosis by polymerase chain reaction.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0882-0546
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
197-205
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The role of mycobacteria in the pathogenesis of sarcoidosis.
pubmed:affiliation
Faculté de Médecine Xavier Bichat, Institut National de la Santé et de la Recherche Médicale, Paris, France.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't