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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1998-10-20
|
| pubmed:abstractText |
We evaluated left and right ventricular diastolic functions by pulsed Doppler echocardiography in 16 children with dilated cardiomyopathy and in 20 healthy age-matched control subjects. The cardiomyopathy group demonstrated an abnormal relaxation pattern of the left ventricle. In the cardiomyopathy group compared to normal subjects, peak early filling velocities (43.3 +/- 11 cm/s versus 60.4 +/- 11 cms/s, p < 0.01), the corresponding velocity-time integrals (3.3 +/- 1.4 cm versus 4.6 +/- 1.2 cm, p < 0.01) and the ratio of peak early filling velocity to late filling velocity (1.22 +/- 0.47 versus 1.49 +/- 0.23, p < 0.05) were significantly lower whereas isovolumic relaxation time was significantly longer (58.9 +/- 19.8 ms versus 49.7 +/- 8.9 ms, p < 0.05). In addition, right ventricular diastolic filling was also impaired in children with dilated cardiomyopathy. Peak early filling velocities (41 +/- 7.9 cm/s versus 47.5 +/- 8.8 cm/s, p < 0.05) and the corresponding velocity time integrals (3.0 +/- 1.0 cm versus 3.87 +/- 1.1 cm, p < 0.05) were significantly decreased, while isovolumic relaxation time was significantly increased (60.6 +/- 16.3 ms versus 52.2 +/- 12.8 ms, p < 0.05) in the cardiomyopathy group. The study suggests that abnormalities of both right and left ventricular diastolic function may occur, and should be searched for, in pediatric patients with dilated cardiomyopathy.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0041-4301
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
40
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
337-46
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9763897-Adolescent,
pubmed-meshheading:9763897-Cardiomyopathy, Dilated,
pubmed-meshheading:9763897-Child,
pubmed-meshheading:9763897-Child, Preschool,
pubmed-meshheading:9763897-Echocardiography, Doppler, Pulsed,
pubmed-meshheading:9763897-Female,
pubmed-meshheading:9763897-Humans,
pubmed-meshheading:9763897-Infant,
pubmed-meshheading:9763897-Male,
pubmed-meshheading:9763897-Ventricular Function, Left,
pubmed-meshheading:9763897-Ventricular Function, Right
|
| pubmed:articleTitle |
Echocardiographic assessment of left and right ventricular diastolic functions in children with dilated cardiomyopathy.
|
| pubmed:affiliation |
Department of Pediatrics, Hacettepe University, Faculty of Medicine, Ankara.
|
| pubmed:publicationType |
Journal Article
|