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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-11-6
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pubmed:abstractText |
Liver regeneration occurs promptly after partial hepatectomy, although the factors regulating this response have not been fully clarified. Molecular events in the regenerative response have been widely characterized after 70% hepatectomy which represents a model of "normal" liver regeneration in rats. More extensive resection results in hepatic failure which has been attributed to a critical loss of hepatic mass. It is not known whether the pattern of genes expressed early in regeneration remains intact after lethal hepatectomy. We hypothesize that the increased expression of selected early response genes remains intact after massive hepatectomy. The aim of this study was to compare the expression of selected genes after 70 and 85% hepatectomy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-4804
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 1998 Academic Press.
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pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
103-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9758723-Animals,
pubmed-meshheading:9758723-Gene Expression,
pubmed-meshheading:9758723-Genes, Immediate-Early,
pubmed-meshheading:9758723-Genes, fos,
pubmed-meshheading:9758723-Genes, myc,
pubmed-meshheading:9758723-Hepatectomy,
pubmed-meshheading:9758723-Hepatocyte Growth Factor,
pubmed-meshheading:9758723-Liver Regeneration,
pubmed-meshheading:9758723-Male,
pubmed-meshheading:9758723-Postoperative Period,
pubmed-meshheading:9758723-Rats,
pubmed-meshheading:9758723-Rats, Wistar
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pubmed:year |
1998
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pubmed:articleTitle |
Early gene expression associated with regeneration is intact after massive hepatectomy in rats.
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pubmed:affiliation |
Liver Transplant Program, University of California, San Francisco, California 94143, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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