| pubmed-article:9753739 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0085187 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0001407 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0010843 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C1704332 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C1514562 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0039679 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:9753739 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:9753739 | pubmed:issue | 20 | lld:pubmed |
| pubmed-article:9753739 | pubmed:dateCreated | 1998-12-7 | lld:pubmed |
| pubmed-article:9753739 | pubmed:abstractText | The cytosine-rich strand of the Tetrahymena telomere consists of multiple repeats of sequence d(AACCCC). We have solved the crystal structure of the crystalline repeat sequence at 2.5 A resolution. The adenines form two different and previously unknown clusters (A clusters) in orthogonal directions with their counterparts from other strands, each containing a total of eight adenines. The clusters appear to be stable aggregates held together by base stacking and three different base-pairing modes. Two different types of cytosine tetraplexes are found in the crystal. Each four-stranded complex is composed of two intercalated parallel-stranded duplexes pointing in opposite directions, with hemiprotonated cytosine-cytosine (C.C+) base pairs. The outermost C.C+base pairs are from the 5'-end of each strand in one cytosine tetraplex and from the 3'-end of each strand in the other. The A clusters and the cytosine tetraplexes form two alternating stacking patterns, creating continuous base stacking in two perpendicular directions along the x - and z -axes. The adenine clusters could be organizational motifs for macromolecular RNA. | lld:pubmed |
| pubmed-article:9753739 | pubmed:keyword | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9753739 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9753739 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9753739 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9753739 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9753739 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9753739 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9753739 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:9753739 | pubmed:issn | 0305-1048 | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:RichAA | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:ChenLL | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:CauPP | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:RaghavanSS | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:MoyzisRR | lld:pubmed |
| pubmed-article:9753739 | pubmed:author | pubmed-author:RatliffRR | lld:pubmed |
| pubmed-article:9753739 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9753739 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:9753739 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:9753739 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9753739 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9753739 | pubmed:pagination | 4696-705 | lld:pubmed |
| pubmed-article:9753739 | pubmed:dateRevised | 2008-11-20 | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
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| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:meshHeading | pubmed-meshheading:9753739-... | lld:pubmed |
| pubmed-article:9753739 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9753739 | pubmed:articleTitle | Intercalated cytosine motif and novel adenine clusters in the crystal structure of the Tetrahymena telomere. | lld:pubmed |
| pubmed-article:9753739 | pubmed:affiliation | Department of Biology, Room 68-233, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. | lld:pubmed |
| pubmed-article:9753739 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9753739 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9753739 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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