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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1998-12-8
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pubmed:databankReference |
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pubmed:abstractText |
Phosducin binds tightly to the beta gamma subunits (Gt beta gamma) of the heterotrimeric G protein transducin, preventing Gt beta gamma reassociation with Gt alpha-GDP and thereby inhibiting the G-protein cycle. Phosducin-like proteins appear to be widely distributed and may play important roles in regulating many heterotrimeric G-protein signaling pathways.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0969-2126
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
6
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1007-19
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:9739091-Amino Acid Sequence,
pubmed-meshheading:9739091-Animals,
pubmed-meshheading:9739091-Cattle,
pubmed-meshheading:9739091-Crystallography, X-Ray,
pubmed-meshheading:9739091-Eye Proteins,
pubmed-meshheading:9739091-GTP-Binding Protein Regulators,
pubmed-meshheading:9739091-GTP-Binding Proteins,
pubmed-meshheading:9739091-Models, Molecular,
pubmed-meshheading:9739091-Molecular Sequence Data,
pubmed-meshheading:9739091-Phosphoproteins,
pubmed-meshheading:9739091-Protein Binding,
pubmed-meshheading:9739091-Protein Conformation,
pubmed-meshheading:9739091-Protein Prenylation,
pubmed-meshheading:9739091-Protein Structure, Secondary,
pubmed-meshheading:9739091-Retina,
pubmed-meshheading:9739091-Sequence Alignment,
pubmed-meshheading:9739091-Signal Transduction,
pubmed-meshheading:9739091-Transducin
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pubmed:year |
1998
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pubmed:articleTitle |
Phosducin induces a structural change in transducin beta gamma.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, University of Illinois at Chicago, IL 60612-7334, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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