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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1976-12-3
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pubmed:abstractText |
Treatment of 12 hypertensive patients with a new imidazoline derivative, St 600 (1.5 to 12.0 mg daily over at least 7 days) resulted in a significant lowering of the blood pressure, mostly to normal values, parallelled by a reduced heart heart rate. A significant decrease in arterial resistance was observed at rest and during exercise in 6 of the patients, whereas a slight increase or no change was recorded in the remaining 6 patients. The changes in resistance in the pulmonary circulation were analogous to those in the systematic circulation for the 2 groups, respectively. The latter half of the patients displayed a decrease in stroke volume, cardiac index and oxygen consumption. No negative inotropic effect was observed.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
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pubmed:issn |
0043-5325
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-206
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:973381-Adult,
pubmed-meshheading:973381-Aged,
pubmed-meshheading:973381-Antihypertensive Agents,
pubmed-meshheading:973381-Blood Pressure,
pubmed-meshheading:973381-Drug Evaluation,
pubmed-meshheading:973381-Female,
pubmed-meshheading:973381-Heart Rate,
pubmed-meshheading:973381-Hemodynamics,
pubmed-meshheading:973381-Humans,
pubmed-meshheading:973381-Hypertension,
pubmed-meshheading:973381-Imidazoles,
pubmed-meshheading:973381-Male,
pubmed-meshheading:973381-Middle Aged
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pubmed:year |
1976
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pubmed:articleTitle |
[A new antihypertensive imidazoline derivative (St 600, Fluoronidine): I. Haemodynamic investigations at rest and during exercise (author's transl)].
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pubmed:publicationType |
Journal Article,
English Abstract
|