rdf:type |
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lifeskim:mentions |
|
pubmed:issue |
7
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pubmed:dateCreated |
1998-9-30
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pubmed:abstractText |
The effects of two polyunsaturated fatty acids, 18:4n-3 and 16:4n-3 purified from the marine algae, Undaria pinnatifida and Ulva pertusa, on icosanoid production in MC/9 mouse mast cells were assessed. Both fatty acids suppressed the production of leukotriene B4 (LTB4), leukotriene C4 (LTC4), and 5-hydroxyeicosatetraenoic acid (5-HETE). The order of the suppressive activity for the two marine algae-derived fatty acids and three other common polyunsaturated fatty acids was as follows; 22:6n-3 = 18:4n-3 = 18:3n-3 > 20:5n-3 = 16:4n-3 for LTB4; 22:6n-3 = 18:4n-3 = 18:3n-3 > 16:4n-3 > 20:5n-3 (no suppression) for LTC4; 22:6n-3 = 18:4n-3 > 18:3n-3 > 20:5n-3 = 16:4n-3 for 5-HETE.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/5-hydroxy-6,8,11,14-eicosatetraenoic...,
http://linkedlifedata.com/resource/pubmed/chemical/Calcimycin,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Unsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxyeicosatetraenoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Ionophores,
http://linkedlifedata.com/resource/pubmed/chemical/Leukotriene B4,
http://linkedlifedata.com/resource/pubmed/chemical/Leukotriene C4,
http://linkedlifedata.com/resource/pubmed/chemical/parinaric acid
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0916-8451
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
62
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
1412-5
|
pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:9720225-Animals,
pubmed-meshheading:9720225-Calcimycin,
pubmed-meshheading:9720225-Chromatography, High Pressure Liquid,
pubmed-meshheading:9720225-Eukaryota,
pubmed-meshheading:9720225-Fatty Acids, Unsaturated,
pubmed-meshheading:9720225-Hydroxyeicosatetraenoic Acids,
pubmed-meshheading:9720225-Ionophores,
pubmed-meshheading:9720225-Leukotriene B4,
pubmed-meshheading:9720225-Leukotriene C4,
pubmed-meshheading:9720225-Mast Cells,
pubmed-meshheading:9720225-Mice,
pubmed-meshheading:9720225-Plants, Edible
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pubmed:year |
1998
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pubmed:articleTitle |
Inhibition of icosanoid production in MC/9 mouse mast cells by n-3 polyunsaturated fatty acids isolated from edible marine algae.
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pubmed:affiliation |
Marine Biochemistry Division, National Research Institute of Fisheries Science, Yokohama, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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