Linked Life Data

9718073

Source:http://linkedlifedata.com/resource/pubmed/id/9718073

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-9-15
pubmed:abstractText
The activity of luciferase expressed in transfected 34i cells has been monitored under 50Hz EMF and heat shock. While heat shock decreased the luciferase activity, short exposure to EMFs did not, the luciferase expressed in cells exposed to EMFs at 300-3000 microT showing the same activity as that of control cells. To further analyse whether EMF and thermal stress display similar effects, the relative rate of Hsp90 and Hsp70 synthesis was investigated. Hsp90 and Hsp70 synthesis, while induced by a short thermal stress, was not increased by EMF exposure. These results, contrary to previously proposed similarities between thermal stress and EMF effects at a cellular level, indicate that protein denaturation and misfolding caused by thermal stress and responsible both for a loss of luciferase activity and for an induction of Hsp, are not necessarily induced by exposure to EMFs.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0024-3205
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
489-97
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Luciferase activity and synthesis of Hsp70 and Hsp90 are insensitive to 50Hz electromagnetic fields.
pubmed:affiliation
INSERM U33, Le Kremlin-Bicêtre, France.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't