Linked Life Data

9717053

Source:http://linkedlifedata.com/resource/pubmed/id/9717053

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1998-12-3
pubmed:abstractText
It has been proposed that alterations of the balance between programmed cell death and cell replication might be involved in abnormalities of smooth muscle cell growth in arterial hypertension. This study was designed to analyse some regulators of apoptosis and proliferation in smooth muscle cells of small intra-myocardial arteries from the left ventricle of adult normotensive Wistar-Kyoto rats (WKY) and adult spontaneously hypertensive rats (SHR). Therefore, we assessed the expression of the cytoplasmic proteins Bax and Bcl-2, respectively a promoter and an inhibitor of apoptosis, and the expression of cyclin A, a nuclear protein that induces proliferation of smooth muscle cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0195-668X
pubmed:author
pubmed:issnType
Print
pubmed:volume
19 Suppl G
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
G29-33
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Altered regulation of smooth muscle cell proliferation and apoptosis in small arteries of spontaneously hypertensive rats.
pubmed:affiliation
Vascular Pathophysiology Unit, School of Medicine, University of Navarra, Pamplona, Spain.
pubmed:publicationType
Journal Article