Linked Life Data

9713654

Source:http://linkedlifedata.com/resource/pubmed/id/9713654

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-9-21
pubmed:abstractText
Paraquat and Yellow Phosphorus are toxic substances that ingested, accidentally or for suicidal intentions, produce a high morbimortality usually associated to the resultant hepatic necrosis. We performed an experimental study to evaluate the protector effect of Interferon in intoxicated rats with these two substances. Rats were divided in groups that only received the toxic (Paraquat or Yellow Phosphorus) and other groups that receive both the toxic and Interferon. The results showed a higher survival rate in the groups treated with Interferon, which was more than 20%. Also, the histopathologic findings showed a hepatic protector effect that was more than 90% in the rats that received Interferon. Clinically, Paraquat was more toxic than Yellow Phosphorus. These favorable experimental results obtained with the use of Interferon will need more research in the future to evaluate its usefulness in the treatment of these intoxications.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-9033
pubmed:author
pubmed:issnType
Print
pubmed:volume
28
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
189-92
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Use of interferon in hepatic necrosis produced by paraquat and yellow phosphorus: experimental evaluation].
pubmed:affiliation
Unidad Gastroenterológica Fundación Esperanza Hospital-Clínica Kennedy, Guayaquil, Ecuador.
pubmed:publicationType
Journal Article, English Abstract