A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells.

Source:http://linkedlifedata.com/resource/pubmed/id/9707591

Proc. Natl. Acad. Sci. U.S.A. 1998 Aug 18 95 17 10009-14

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PMID
9707591