Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1976-11-21
pubmed:abstractText
Twenty-one asthmatic patients participated in a single blind, crossover study comparing the effects of aerosol and oral salbutamol (a beta-adrenergic bronchodilator), on exercise-induced bronchospasm. By both routes of administration, salbutamol (albuterol) produced significant bronchodilatation at rest, but only the aerosol effectively prevented post-exercise bronchospasm in most patients. Because exercise-induced bronchospasm is a common problem in children and adults with asthma, these observations are relevant to the drug therapy of these patients. The existence of separate mechanisms for bronchodilatation and the prevention of exercise-induced asthma is postulated. It is possible that differing tissue concentrations of salbutamol are responsible for the observed differences between the 2 routes of administration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0003-0805
pubmed:author
pubmed:issnType
Print
pubmed:volume
114
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-500
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Inhaled and oral salbutamol in exercise-induced asthma.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Controlled Clinical Trial