|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
1998-10-30
|
|
pubmed:abstractText |
Membranous nephropathy (MN) is a 'non-proliferative' glomerulonephritis. However, visceral glomerular epithelial cell (vGEC) proliferating cell nuclear antigen staining and increased glomerular histone mRNA in passive Heymann nephritis (PHN), suggest that vGECs may enter the cell cycle and undergo DNA synthesis. We used in situ hybridisation for histone mRNA, an S-phase specific marker, to investigate this possibility and identify the cellular origin of histone mRNA in PHN and MN.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1018-7782
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
352-8
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:9690098-Adult,
pubmed-meshheading:9690098-Aged,
pubmed-meshheading:9690098-Animals,
pubmed-meshheading:9690098-Antibodies,
pubmed-meshheading:9690098-Antigens, Thy-1,
pubmed-meshheading:9690098-DNA,
pubmed-meshheading:9690098-Epithelial Cells,
pubmed-meshheading:9690098-Glomerulonephritis,
pubmed-meshheading:9690098-Glomerulonephritis, Membranous,
pubmed-meshheading:9690098-Histones,
pubmed-meshheading:9690098-Humans,
pubmed-meshheading:9690098-Kidney,
pubmed-meshheading:9690098-Kidney Glomerulus,
pubmed-meshheading:9690098-Middle Aged,
pubmed-meshheading:9690098-Proliferating Cell Nuclear Antigen,
pubmed-meshheading:9690098-RNA, Messenger,
pubmed-meshheading:9690098-Rats,
pubmed-meshheading:9690098-Rats, Sprague-Dawley
|
|
pubmed:articleTitle |
Visceral glomerular epithelial cell DNA synthesis in experimental and human membranous disease.
|
|
pubmed:affiliation |
Department of Nephrology, Leicester General Hospital, UK.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|
