rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1998-8-25
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pubmed:abstractText |
The Neurospora crassa con-10 gene is weakly expressed in mycelia but is induced approximately 1000-fold during macroconidiation. Studies of the promoter elements and trans-acting factors that regulate con-10 expression are needed to gain a detailed understanding of developmental regulation. The rco-1 mutant displays a 10-fold elevated basal level of expression of con-10. In contrast to the wild type, con-10 expression in mycelia of the rco-1 mutant was rapidly induced to high levels by starvation for carbon or nitrogen and by heat shock. Although con-10 is developmentally induced late in conidiation, con-10 was inducible by heat shock shortly after exposure of the wild-type mycelium to air. These findings support the view that RCO1 is a cell type-specific repressor of con-10. We propose that inactivation of RCO1 allows developing conidiophores to adjust the timing of con-10 induction in response to stress.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CON-10 protein, Neurospora crassa,
http://linkedlifedata.com/resource/pubmed/chemical/Fungal Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/RCO-1 protein, Neurospora crassa,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Fungal,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Repressor Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1087-1845
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
269-78
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9680957-Amino Acid Sequence,
pubmed-meshheading:9680957-Blotting, Northern,
pubmed-meshheading:9680957-Circadian Rhythm,
pubmed-meshheading:9680957-Fungal Proteins,
pubmed-meshheading:9680957-Gene Expression Regulation, Fungal,
pubmed-meshheading:9680957-Genes, Fungal,
pubmed-meshheading:9680957-Glucose,
pubmed-meshheading:9680957-Heat-Shock Response,
pubmed-meshheading:9680957-Molecular Sequence Data,
pubmed-meshheading:9680957-Neurospora crassa,
pubmed-meshheading:9680957-RNA, Fungal,
pubmed-meshheading:9680957-RNA, Messenger,
pubmed-meshheading:9680957-Repressor Proteins,
pubmed-meshheading:9680957-Time Factors
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pubmed:year |
1998
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pubmed:articleTitle |
Tissue-specific repression of starvation and stress responses of the Neurospora crassa con-10 gene is mediated by RCO1.
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pubmed:affiliation |
Department of Plant Pathology and Microbiology, Texas A&M University, College Station 77843-2132, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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