rdf:type |
|
lifeskim:mentions |
umls-concept:C0013216,
umls-concept:C0018270,
umls-concept:C0027651,
umls-concept:C0039082,
umls-concept:C0087111,
umls-concept:C0443252,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2587213,
umls-concept:C2911692
|
pubmed:issue |
1
|
pubmed:dateCreated |
1998-7-16
|
pubmed:abstractText |
The diencephalic syndrome (DS), which is manifested by progressive emaciation and failure to thrive in an apparently alert, cheerful infant, usually is due to a low grade hypothalamic glioma. Treatment with aggressive surgery and/or radiotherapy is variably successful in controlling disease and may result in severe neurologic sequelae. Chemotherapy recently has been shown to be effective in patients with low grade gliomas of childhood, but it is used infrequently in those with DS.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0008-543X
|
pubmed:author |
pubmed-author:BroxsonE HEHJr,
pubmed-author:FinlayJJ,
pubmed-author:GeyerRR,
pubmed-author:GropmanA LAL,
pubmed-author:JakackiRR,
pubmed-author:NeedleMM,
pubmed-author:NicholsonH SHS,
pubmed-author:OlsonJ MJM,
pubmed-author:PackerR JRJ,
pubmed-author:PhillipsPP,
pubmed-author:ReamanGG,
pubmed-author:VezinaL GLG
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
166-72
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9655307-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9655307-Brain Neoplasms,
pubmed-meshheading:9655307-Carboplatin,
pubmed-meshheading:9655307-Emaciation,
pubmed-meshheading:9655307-Failure to Thrive,
pubmed-meshheading:9655307-Female,
pubmed-meshheading:9655307-Glioma,
pubmed-meshheading:9655307-Humans,
pubmed-meshheading:9655307-Infant,
pubmed-meshheading:9655307-Male,
pubmed-meshheading:9655307-Syndrome,
pubmed-meshheading:9655307-Vincristine
|
pubmed:year |
1998
|
pubmed:articleTitle |
Treatment of diencephalic syndrome with chemotherapy: growth, tumor response, and long term control.
|
pubmed:affiliation |
Department of Neurology, Children's National Medical Center and George Washington University, Washington, DC 20010, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|