rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2-3
|
pubmed:dateCreated |
1998-6-29
|
pubmed:abstractText |
The time relationship between DTP immunization and infantile spasms (IS) onset was examined using three models--association, temporal shift, and no-effect--and the case/control data from the National Childhood Encephalopathy Study (NCES). Infantile spasms cases classified as being previously abnormal (e.g., tuberous sclerosis complex patients) showed a no-effect relationship, whereas those classified as previously normal suggested a fit to the temporal shift model, i.e. no increase in number of cases but a shortening of time to onset of seizure. No data fit the association model. Analyses for vaccine complications should examine for temporal changes (i.e. temporal shift) in addition to increased risks.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0264-410X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
16
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
225-31
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9607034-Child, Preschool,
pubmed-meshheading:9607034-Diphtheria Toxoid,
pubmed-meshheading:9607034-Diphtheria-Tetanus Vaccine,
pubmed-meshheading:9607034-Diphtheria-Tetanus-Pertussis Vaccine,
pubmed-meshheading:9607034-Female,
pubmed-meshheading:9607034-Great Britain,
pubmed-meshheading:9607034-Humans,
pubmed-meshheading:9607034-Immunization,
pubmed-meshheading:9607034-Infant,
pubmed-meshheading:9607034-Male,
pubmed-meshheading:9607034-Spasms, Infantile,
pubmed-meshheading:9607034-Tetanus Toxoid,
pubmed-meshheading:9607034-Time Factors,
pubmed-meshheading:9607034-Vaccines, Combined
|
pubmed:articleTitle |
Temporal relationship modeling: DTP or DT immunizations and infantile spasms.
|
pubmed:affiliation |
Johns Hopkins University School of Public Health, Washington, DC 20007, USA.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.
|