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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1998-6-24
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pubmed:abstractText |
The objective of this study was to develop an MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint at high spatial and temporal resolution. A nonmetallic pressure device was constructed for applying loads of >1000 N to a femoro-patellar articulation within an extremity coil of a clinical 1.5 T MRI scanner. Digital image processing methods were used to determine the location- and time-dependent cartilage deformation in consecutive 2D fat-suppressed FLASH images. Additionally, three-dimensional reconstruction of the cartilage was performed from 3D fat-suppressed FLASH image data. During the first 10 min of static compression, thickness changes between 10 and 30% were observed. Thickness changes greater than 50% and volume changes of 20% were recorded after 3 h. The technique permits analysis of the load and time-dependent mechanical behavior of articular cartilage in its natural environment.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0740-3194
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
843-50
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9581616-Adult,
pubmed-meshheading:9581616-Cadaver,
pubmed-meshheading:9581616-Cartilage, Articular,
pubmed-meshheading:9581616-Female,
pubmed-meshheading:9581616-Humans,
pubmed-meshheading:9581616-Image Processing, Computer-Assisted,
pubmed-meshheading:9581616-Knee Joint,
pubmed-meshheading:9581616-Magnetic Resonance Imaging,
pubmed-meshheading:9581616-Male,
pubmed-meshheading:9581616-Weight-Bearing
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pubmed:year |
1998
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pubmed:articleTitle |
An MR-based technique for quantifying the deformation of articular cartilage during mechanical loading in an intact cadaver joint.
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pubmed:affiliation |
Anatomische Anstalt, Ludwig Maximilians Universität München, Germany.
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pubmed:publicationType |
Journal Article
|