Linked Life Data

9560883

Source:http://linkedlifedata.com/resource/pubmed/id/9560883

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-5-19
pubmed:abstractText
The determination of benzodiazepine derivatives lorazepam and lormetazepam in urine is based on detection of their metabolites 2-amino-2',5-dichlorobenzophenone and 2-methylamino-2'5-dichlorbenzophenone in hydrolyzed urine. Both substances are structurally very similar to the metabolites of diazepam 2-amino-5-chlorbenzophenone and 2-methylamino-5-chlorbenzophenone and their mobility on thin layer chromatograms is similar as well. This could cause their confusion and misinterpretation of the results. Therefore suitable combination of mobile phases and thin layer plates was sought in this study for the unambiguous identification of respective benzophenones by thin layer chromatography.
pubmed:language
cze
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0371-1854
pubmed:author
pubmed:issnType
Print
pubmed:volume
43
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Detection of lorazepam and lormetazepam metabolites in urine using thin-layer chromatography].
pubmed:affiliation
Ustav pro toxikologii a soudní chemii 1. LF UK a VFN, Praha.
pubmed:publicationType
Journal Article, English Abstract