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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1998-5-21
|
| pubmed:abstractText |
According to the guidelines of the "Third international workshop conference on GDM", we have examined 2000 pregnant women. The glucose challenge test (GCT) was positive in 408 cases (20.4%) and negative in 1592 (79.6%). The OGTT (Carpenter and Coustan's criteria) was performed in 647 pregnant women. GDM and IGGT prevalence was of 6.25% and 5.5% respectively and normal glucose tolerance (NGT) 88.25%. The GCT effectiveness for GDM and IGGT diagnosis is: sensibility 75.1%, specificity 44%, positive predictive value 46.4% and negative predictive value 74%. GDM and IGGT compared with NGT women were significantly older (p < 0.05) and prepregnancy BMI was higher (p < 0.01); the prevalence of previous macrosomia (p < 0.01), previous gestational diabetes (p < 0.01) and family history for diabetes mellitus (p < 0.05) was greater in GDM and IGCT. The prevalence of preterm delivery was higher in both GDM and IGCT (GDM 12.5% and IGGT 15.4% vs NGT 6%; p < 0.01), as well as the prevalence of cesarean sections (GDM 31.6% vs IGGT 23.5% and NGT 20.3%; p < 0.02), and the occurrence of macrosomia (GDM 27.6%, IGGT 16.6% and NGT 16.2%). In addition a higher prevalence (p < 0.01) of hyperbilirubinaemia, hypoglycemia and hypertrophy cardiomyopathy was observed in newborns from GDM women. Our data show that: GCT has a good specificity for GDM diagnosis, prevalence of GDM in our population is about 6%, GDM is still correlated to an elevated maternal and neonatal morbility.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0021-2571
|
| pubmed:author |
pubmed-author:BenziLL,
pubmed-author:BottonePP,
pubmed-author:CasadidioII,
pubmed-author:Di CarloAA,
pubmed-author:Di CianniGG,
pubmed-author:FantoniMM,
pubmed-author:FontanaGG,
pubmed-author:LuchiCC,
pubmed-author:MalaraNN,
pubmed-author:MarselliLL,
pubmed-author:NavalesiRR,
pubmed-author:OrsiniPP,
pubmed-author:RossiLL,
pubmed-author:TetiGG,
pubmed-author:TrifiròRR,
pubmed-author:VillaniGG,
pubmed-author:VolpeLL
|
| pubmed:issnType |
Print
|
| pubmed:volume |
33
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
389-91
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading | |
| pubmed:year |
1997
|
| pubmed:articleTitle |
Screening of gestational diabetes in Tuscany: results in 2000 cases.
|
| pubmed:affiliation |
Cattedra di Malattie del Metabolismo, Azienda Ospedaliera, Università degli Studi, Pisa, Italy.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial
|