| pubmed-article:9534987 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0206178 | lld:lifeskim |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0021051 | lld:lifeskim |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0544452 | lld:lifeskim |
| pubmed-article:9534987 | lifeskim:mentions | umls-concept:C0677908 | lld:lifeskim |
| pubmed-article:9534987 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:9534987 | pubmed:dateCreated | 1998-4-21 | lld:pubmed |
| pubmed-article:9534987 | pubmed:abstractText | Seven AIDS patients who were receiving suppressive therapy for previously diagnosed cytomegalovirus (CMV) retinitis were offered treatment with protease inhibitors (PIs). Secondary prophylaxis for CMV was discontinued after 3 months of therapy with PIs if patients had >150 CD4 cells/mm3 and a human immunodeficiency virus (HIV) load of <200 copies/mL and if they were negative for CMV as determined by qualitative CMV polymerase chain reaction (PCR). Ophthalmologic exams were done periodically. After a median follow-up of 9 months (range, 9-12), no new episodes of CMV retinitis were observed. CD4 cell counts were >150 cells/mm3 in all cases, HIV loads were <200 copies/mL, and results for qualitative CMV PCRs remained negative. These observations suggest that for selected patients with healed CMV retinitis who have immunologic and virologic evidence of a clinical response to potent combination antiretroviral therapy, temporary discontinuation of a chronic anti-CMV suppressive therapy may not result in further retinal necrosis. However, the long-term immunologic benefit of PIs and hence the safety of prolonged withdrawal of anti-CMV therapy is unknown. | lld:pubmed |
| pubmed-article:9534987 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9534987 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9534987 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:9534987 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9534987 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9534987 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9534987 | pubmed:issn | 0022-1899 | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:JogSS | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:RuizSS | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:RomeuJJ | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:ClotetBB | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:AndresFF | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:RuizLL | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:TuranAA | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:SireraGG | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:ArnóAA | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:ConejeroMM | lld:pubmed |
| pubmed-article:9534987 | pubmed:author | pubmed-author:BonjochAA | lld:pubmed |
| pubmed-article:9534987 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9534987 | pubmed:volume | 177 | lld:pubmed |
| pubmed-article:9534987 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9534987 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9534987 | pubmed:pagination | 1080-3 | lld:pubmed |
| pubmed-article:9534987 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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| pubmed-article:9534987 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9534987 | pubmed:articleTitle | Long-lasting remission of cytomegalovirus retinitis without maintenance therapy in human immunodeficiency virus-infected patients. | lld:pubmed |
| pubmed-article:9534987 | pubmed:affiliation | Ophthalmologic Department, Germans Trias i Pujol University Hospital, Badalona, Spain. | lld:pubmed |
| pubmed-article:9534987 | pubmed:publicationType | Journal Article | lld:pubmed |
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