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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-4-30
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pubmed:abstractText |
To determine the effect of extending the duration of ammonia (2% dry matter basis) treatment ti'om 1 to 5 wk on the toxicity of endophyte-infected tall fescue seed, 60 male Harlan Sprague-Dawley rats were randomly assigned to the following six treatments during a 28-d trial: endophyte-free (E-), endophyte-infected (E+), 1 wk ammoniated endophyte-fee (1AE-), 1 wk ammoniated endophyte-infected (1AE+), 5 wk ammoniated endophyte-free (5AE-), and 5 wk ammoniated endophyte-infected (5AE+) tall fescue seed. The concentration of total pyrrolizidine alkaloids (N-acetyl and N-formyl loline) or E+ rescue was reduced from 4203 12 g/g to 3009 and 2533 I-tg/g by the 1AE+ and 5AE+ treatments, respectively. Ergovaline was lowered from 3.77 to 1.57 12 g/g by 1AE+ and eliminated by 5AE+. Endophyte-infected treatment groups had depressed (P < 0.0001) dally feed intakes (DFI), daily weight gains (DWG), feed efficiencies (G/F), primary antibody responses, and T cell and B cell mitogenic responses than endophyte-free treatment groups. Ammoniation of endophyte-infected rescue seed improved DFI and DWG (P < 0.0001) and G/F (P < 0.05); however, there was no difference in performance criteria between the 1-wk and 5-wk ammoniation treatments. Endophyte-induced depressions in immune function were not alleviated by ammoniation.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0148-0545
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-95
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9530533-Acremonium,
pubmed-meshheading:9530533-Ammonia,
pubmed-meshheading:9530533-Animals,
pubmed-meshheading:9530533-Body Weight,
pubmed-meshheading:9530533-Hemagglutination Tests,
pubmed-meshheading:9530533-Lymphocyte Activation,
pubmed-meshheading:9530533-Male,
pubmed-meshheading:9530533-Organ Size,
pubmed-meshheading:9530533-Plant Poisoning,
pubmed-meshheading:9530533-Poaceae,
pubmed-meshheading:9530533-Pyrrolizidine Alkaloids,
pubmed-meshheading:9530533-Rats,
pubmed-meshheading:9530533-Rats, Sprague-Dawley,
pubmed-meshheading:9530533-Seeds,
pubmed-meshheading:9530533-Sheep,
pubmed-meshheading:9530533-Spleen
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pubmed:year |
1998
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pubmed:articleTitle |
Comparison of two ammoniation procedures to reduce the toxicity of endophyte-infected tall fescue seed fed to rats.
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pubmed:affiliation |
Department of Animal Sciences, University of Kentucky Lexington 40546, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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