Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
1998-5-7
pubmed:databankReference
pubmed:abstractText
The nucleotide sequences of the putative proA and proB genes of Treponema pallidum were determined. The proA gene is 1287 nucleotides long and encodes a 428 amino acid protein with a predicted M(r) of 46.6 kDa. The proB gene is 891 nucleotides long and encodes a 296 amino acid protein with a predicted M(r) of 31.3 kDa. The deduced amino acid sequences of the treponemal ProA and ProB proteins have a high degree of homology to the amino acid sequences of several bacterial ProA and ProB proteins. The order of the T. pallidum pro genes (proA/proB) is unique in comparison to the order of these genes in other bacteria. The identification of the putative proA and proB genes in T. pallidum, coupled with the previous identification of the proC gene, strongly suggests that this fastidious spirochete is capable of proline biosynthesis.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1042-5179
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
63-70
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Nucleotide sequences of the proA and proB genes of Treponema pallidum, the syphilis agent.
pubmed:affiliation
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill 27599-7400, USA. lstamm@email.unc.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.