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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-5-20
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pubmed:abstractText |
Rats with extensive ibotenic acid lesions centered in the gustatory zone of the pontine parabrachial nucleus (PBN) failed to acquire a conditioned taste aversion (CTA) induced by lithium chloride (LiCl) toxicosis (Experiments 1 and 4). This deficit cannot be explained as an inability to either perceive or process gustatory information because lesioned rats that failed to acquire a CTA readily acquired a conditioned flavor preference (Experiment 2). Similarly, the CTA deficit cannot be attributed to an inability to experience or process visceral input because PBN-lesioned rats that failed to acquire a CTA successfully learned an aversion to a trigeminal stimulus, capsaicin, when paired with LiCl-induced illness (Experiment 3). This pattern of results supports the view that cell bodies within the PBN are essential for the associative processes that govern CTA learning.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0735-7044
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
112
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
160-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9517824-Animals,
pubmed-meshheading:9517824-Association Learning,
pubmed-meshheading:9517824-Avoidance Learning,
pubmed-meshheading:9517824-Brain Mapping,
pubmed-meshheading:9517824-Capsaicin,
pubmed-meshheading:9517824-Conditioning, Classical,
pubmed-meshheading:9517824-Ibotenic Acid,
pubmed-meshheading:9517824-Lithium Chloride,
pubmed-meshheading:9517824-Male,
pubmed-meshheading:9517824-Mental Recall,
pubmed-meshheading:9517824-Pons,
pubmed-meshheading:9517824-Rats,
pubmed-meshheading:9517824-Rats, Sprague-Dawley,
pubmed-meshheading:9517824-Solitary Nucleus,
pubmed-meshheading:9517824-Taste,
pubmed-meshheading:9517824-Trigeminal Nerve
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pubmed:year |
1998
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pubmed:articleTitle |
Ibotenic acid lesions of the parabrachial nucleus and conditioned taste aversion: further evidence for an associative deficit in rats.
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pubmed:affiliation |
Department of Behavioral Science, College of Medicine, Pennsylvania State University, Hershey 17033, USA. psg6@psu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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