| pubmed-article:9517683 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C0374711 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C0043240 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C0043246 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C0040464 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C1705181 | lld:lifeskim |
| pubmed-article:9517683 | lifeskim:mentions | umls-concept:C0761379 | lld:lifeskim |
| pubmed-article:9517683 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9517683 | pubmed:dateCreated | 1998-4-7 | lld:pubmed |
| pubmed-article:9517683 | pubmed:abstractText | The effectiveness of two new topical anesthetics that do not contain cocaine (prilocaine-phenylephrine and bupivacaine-phenylephrine) was compared with that of tetracaine-adrenaline-cocaine (TAC) during laceration repair in children. This study was a prospective, randomized, double-blind trial conducted in the emergency department of a large children's hospital. Participants were 180 children 1 year of age or older with a laceration 5 cm or less in length that required suturing. Pain felt during suturing was scored by suture technicians, research assistants, parents, and patients 5 years of age and older using a visual analogue scale (VAS). There was no statistical difference demonstrated between the effectiveness of prilocaine-phenylephrine and that of TAC for any of the observer groups. A statistically significant difference was seen among anesthetics when comparing VAS scores of research assistants (P = .002), suture technicians (P = .006), and parents (P = .03), but not when comparing VAS ratings of patients (P = .07). Based on Tukey's post hoc test, these statistically significant differences were between TAC and bupivacaine-phenylephrine. When power analyses were performed using alpha = 0.05 and beta = 0.20, it was possible to detect a difference of 1.3 VAS units for each rater group. In conclusion, this study demonstrated the effectiveness and safety of prilocaine-phenylephrine and bupivacaine-phenylephrine. Prilocaine-phenylephrine statistically outperformed bupivacaine-phenylephrine and offers an effective alternative to TAC during laceration repair in children. | lld:pubmed |
| pubmed-article:9517683 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9517683 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9517683 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9517683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9517683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9517683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9517683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9517683 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9517683 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9517683 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:9517683 | pubmed:issn | 0735-6757 | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:SmithG AGA | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:CohenD MDM | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:BarrettTT | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:PowersJ DJD | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:ShieldsB JBJ | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:StrausbaughS... | lld:pubmed |
| pubmed-article:9517683 | pubmed:author | pubmed-author:Harbeck-Weber... | lld:pubmed |
| pubmed-article:9517683 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9517683 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:9517683 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9517683 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9517683 | pubmed:pagination | 121-4 | lld:pubmed |
| pubmed-article:9517683 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:9517683 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9517683 | pubmed:articleTitle | Prilocaine-phenylephrine and bupivacaine-phenylephrine topical anesthetics compared with tetracaine-adrenaline-cocaine during repair of lacerations. | lld:pubmed |
| pubmed-article:9517683 | pubmed:affiliation | Department of Pediatrics, The Ohio State University College of Medicine, Columbus, USA. | lld:pubmed |
| pubmed-article:9517683 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9517683 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:9517683 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:9517683 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
| pubmed-article:9517683 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9517683 | lld:pubmed |
