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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1976-10-2
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pubmed:abstractText |
Groups of day-old chicks with varying levels of parental antibody were vaccinated against Newcastle disease (B1 strain) with a commercially available device which simultaneously debeaks the chick and emits a fine spray of vaccine into its trachea. Some groups were also vaccinated (B1 or Lasota strain) with a commercially available vaccine sprayer at 9 days, 14 days, or 9 and 25 days of age. Response to vaccine was evaluated once each week during the experimental period of approximately 8 weeks HI titers were determined and 10 chicks were challenged with the Texas GB strain of Newcastle disease virus. In chicks with low to moderate levels of maternal antibody a satisfactory antibody response was attained by vaccination at 1 day of age, and in most cases resistance to challenge was evident by 3 weeks of age. Intratracheal vaccination of chicks with extremely high levels of maternal antibody had a minimal antibody response. All groups of chicks spray vaccinated at 9, 14, or 9 and 25 days of age showed a marked increase in antibody titer regardless of whether they had been vaccinated at 1 day of age.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0032-5791
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1252-67
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:951360-Aerosols,
pubmed-meshheading:951360-Age Factors,
pubmed-meshheading:951360-Animals,
pubmed-meshheading:951360-Antibody Formation,
pubmed-meshheading:951360-Chickens,
pubmed-meshheading:951360-Immunity, Maternally-Acquired,
pubmed-meshheading:951360-Newcastle Disease,
pubmed-meshheading:951360-Newcastle disease virus,
pubmed-meshheading:951360-Trachea,
pubmed-meshheading:951360-Viral Vaccines
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pubmed:year |
1976
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pubmed:articleTitle |
Efficacy of intratracheal administration of Newcastle disease vaccine in day-old chicks.
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pubmed:publicationType |
Journal Article
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