Linked Life Data

9504181

Source:http://linkedlifedata.com/resource/pubmed/id/9504181

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-4-10
pubmed:abstractText
The present work describes and analyzes the results of a randomized clinical trial on adolescents (age 18.2 +/- 0.6) carried out in order to evaluate the effects of a twice daily mouthrinse application containing xylitol, sorbitol, sacarine, ciclamate, aspartame, chlorhexidine, hexetidine or NaF for 14 days on amylase, peroxidase, thiocyanate, hypothiocyanite, secretory IgA and total proteins in whole saliva. No significative changes were observed in health and bucodental parameters nor in flow salivary rate, protein, secretory Ig A, or thiocyanate levels as a consequence of the mouthrinses application. On the other hand, NaF treatment (0.02%, 0.05% or 0.1%) did cause an increase in salivary peroxidase and hypothiocyanite, being the former increase higher than the second one. Peroxidase increase was proportional to the mouthrinse dose (r = 0.78; p < 0.01), but not to the hypothiocyanite increase (r = 0.407; p = 0.12). Since the adolescents' health condition was the adequate, it is suggested that the peroxidase increase was due to a higher enzyme synthesis and/or secretion by the parotid and/or submaxillar glands. It is concluded that the increases in salivary peroxidase and hypothiocyanite caused by the NaF treatment favour the host, as they potentiate one of the mechanisms that modulate dental plaque composition, preventing in such a way the colonization by cariogenic pathogens.
pubmed:language
spa
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0327-6309
pubmed:author
pubmed:issnType
Print
pubmed:volume
47
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
211-20
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Effects of local treatment with sodium fluoride mouthrinse on peroxidase and hypothiocyanite saliva levels in adolescent]/.
pubmed:affiliation
Cátedra de Química y Física Biológicas, Facultad de Odontología, UNC, Córdoba, Argentina.
pubmed:publicationType
Journal Article, Clinical Trial, English Abstract, Randomized Controlled Trial, Research Support, Non-U.S. Gov't