Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-4-14
pubmed:databankReference
pubmed:abstractText
The OS-9 gene is frequently amplified in human sarcomas. We isolated and characterized an OS-9 genomic DNA from a human BAC library. Sequencing of the genomic DNA showed that the gene spanned approximately 30.4 kbp and had 15 exons. The 1,010 bp sequence of the 5' upstream region was also determined. The potential binding-sequence motifs TATA and CCAAT for general transcription factors were found in the 5' upstream region. Primer extension analysis revealed two putative transcription start sites. The significance of the 5' upstream sequence in the ubiquitous expression of the OS-9 gene in various tissues and culture cells is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0021-924X
pubmed:author
pubmed:issnType
Print
pubmed:volume
122
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1190-5
pubmed:dateRevised
2007-12-19
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Genomic organization of the OS-9 gene amplified in human sarcomas.
pubmed:affiliation
Graduate School of Integrated Science, Yokohama City University, Yokohama.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't