| pubmed-article:9480855 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0560175 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0596901 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0521447 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0475264 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C1706209 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C1707689 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0439831 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0301869 | lld:lifeskim |
| pubmed-article:9480855 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:9480855 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:9480855 | pubmed:dateCreated | 1998-3-27 | lld:pubmed |
| pubmed-article:9480855 | pubmed:abstractText | Peptides containing a hydrophobic motif associated with a nuclear localization signal separated by various linkers were synthesized in solid phase. The hydrophobic sequence corresponds either to a signal peptide sequence or to a fragment of the fusion peptide of GP41 while the hydrophilic sequence is that of a nuclear localization signal. The C-termini of these peptides bear a cysteamide group that was linked to a fluorescent probe. This allowed the cellular localization of the probe to be determined as a function of the peptide sequences. The labeled peptides were then incubated with fibroblasts. Using N-biotinylated derivatives we confirmed by indirect immunofluorescence that the observed localizations corresponds to those of the peptides. The presence of a linker appears to play a role in the cellular localization. One of these peptides was successfully used to target fluorescent oligodeoxynucleotides into living cells demonstrating improved cell delivery of peptide-oligodeoxynucleotide conjugates. | lld:pubmed |
| pubmed-article:9480855 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9480855 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9480855 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9480855 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:9480855 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9480855 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:9480855 | pubmed:issn | 0006-291X | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:VidalPP | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:HeitzFF | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:MuhrC ECE | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:MéryJJ | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:DivitaGG | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:LautredouNN | lld:pubmed |
| pubmed-article:9480855 | pubmed:author | pubmed-author:ChaloinLL | lld:pubmed |
| pubmed-article:9480855 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9480855 | pubmed:day | 13 | lld:pubmed |
| pubmed-article:9480855 | pubmed:volume | 243 | lld:pubmed |
| pubmed-article:9480855 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9480855 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9480855 | pubmed:pagination | 601-8 | lld:pubmed |
| pubmed-article:9480855 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:9480855 | pubmed:meshHeading | pubmed-meshheading:9480855-... | lld:pubmed |
| pubmed-article:9480855 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9480855 | pubmed:articleTitle | Design of carrier peptide-oligonucleotide conjugates with rapid membrane translocation and nuclear localization properties. | lld:pubmed |
| pubmed-article:9480855 | pubmed:affiliation | Centre de Recherche de Biochimie Macromoléculaire, ERS 155 1919, Montpellier, France. | lld:pubmed |
| pubmed-article:9480855 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9480855 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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