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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1998-4-9
|
| pubmed:abstractText |
The aim of this study was to compare the diagnostic performance of conventional mammography and dynamic contrast-enhanced fast 3D gradient-echo (GRE) MRI regarding the detection and characterization of breast lesions relative to histopathologic analysis and to assess the results of a combined evaluation of both methods. fifty consecutive patients with 63 histopathologically verified breast lesions underwent dynamic contrast-enhanced GRE MRI in addition to routine conventional mammography. All lesions were classified by both methods on a five-point scale as benign or malignant, and the results were correlated to histopathology. Conventional mammography and dynamic MRI yielded a sensitivity and specificity of 82 and 64 %, and 92 and 76 %, respectively. The difference between the results was statistically not significant (p > 0.05) with areas under the receiver-operating-characteristics curves of 0.807 for mammography and 0.906 for MR imaging. Combination of the results of both methods slightly increased the sensitivity for detection of breast cancer to 95 % but decreased specificity to 52 %. In this selected patient subset, including only patients referred for excisional biopsy, contrast-enhanced dynamic MRI proved more sensitive and specific than conventional mammography regarding the detection of malignancy. While a combination of both methods yields a slightly improved sensitivity, specificity is vastly reduced.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Contrast Media,
http://linkedlifedata.com/resource/pubmed/chemical/Gadolinium,
http://linkedlifedata.com/resource/pubmed/chemical/Meglumine,
http://linkedlifedata.com/resource/pubmed/chemical/Organometallic Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/gadoterate meglumine
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0938-7994
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
8
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
194-200
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9477265-Adult,
pubmed-meshheading:9477265-Aged,
pubmed-meshheading:9477265-Aged, 80 and over,
pubmed-meshheading:9477265-Biopsy,
pubmed-meshheading:9477265-Breast,
pubmed-meshheading:9477265-Breast Neoplasms,
pubmed-meshheading:9477265-Contrast Media,
pubmed-meshheading:9477265-False Negative Reactions,
pubmed-meshheading:9477265-Female,
pubmed-meshheading:9477265-Gadolinium,
pubmed-meshheading:9477265-Humans,
pubmed-meshheading:9477265-Magnetic Resonance Imaging,
pubmed-meshheading:9477265-Mammography,
pubmed-meshheading:9477265-Meglumine,
pubmed-meshheading:9477265-Middle Aged,
pubmed-meshheading:9477265-Organometallic Compounds,
pubmed-meshheading:9477265-ROC Curve,
pubmed-meshheading:9477265-Sensitivity and Specificity
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Detection of breast cancer with conventional mammography and contrast-enhanced MR imaging.
|
| pubmed:affiliation |
Department of Diagnostic Radiology, Zurich University Hospital, Rämistrasse 100, CH-8091 Zurich, Switzerland.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|