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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1998-2-24
|
| pubmed:abstractText |
We report four patients with cystic fibrosis and fulminant Clostridium difficile-associated colitis: two died, and one required hemicolectomy. Three of four patients carried the N1303K mutation. Severe and fatal C. difficile colitis can occur in cystic fibrosis patients, possibly with a genotype-specific predilection (i.e., N1303K/other). Because cystic fibrosis patients may have a wide spectrum of gastrointestinal symptoms, disease caused by C. difficile must be considered when these patients have acute abdominal pain, diarrhea, or severe leukocytosis.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0022-3476
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
132
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
177-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9470027-Child,
pubmed-meshheading:9470027-Child, Preschool,
pubmed-meshheading:9470027-Cystic Fibrosis,
pubmed-meshheading:9470027-Enterocolitis, Pseudomembranous,
pubmed-meshheading:9470027-Fatal Outcome,
pubmed-meshheading:9470027-Female,
pubmed-meshheading:9470027-Humans,
pubmed-meshheading:9470027-Male,
pubmed-meshheading:9470027-Mutation
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Severe Clostridium difficile-associated colitis in young patients with cystic fibrosis.
|
| pubmed:affiliation |
Department of Pediatrics, Carmel Medical Center, Haifa, Israel.
|
| pubmed:publicationType |
Journal Article,
Case Reports
|