rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
12
|
pubmed:dateCreated |
1998-4-2
|
pubmed:abstractText |
We performed double high-dose chemotherapy (HDCT) and autologous stem cell rescue (ASCR) on an 8-year-old girl after relapse of Wilms' tumor with unfavorable histology. Relapse occurred while the patient was still on first-line therapy and showed multiple adverse prognostic features. Since depleted hematopoietic reserves restricted further conventional therapy, a double HDCT approach was chosen to achieve maximal dose intensity. Four years after relapse the girl is in second remission and well. Double HDCT with ASCR may represent a feasible approach to rescue extensively pretreated patients with recurrent Wilms' tumor of unfavorable histology.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0268-3369
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
20
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1111-3
|
pubmed:dateRevised |
2006-4-24
|
pubmed:meshHeading |
pubmed-meshheading:9466289-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:9466289-Child,
pubmed-meshheading:9466289-Combined Modality Therapy,
pubmed-meshheading:9466289-Dactinomycin,
pubmed-meshheading:9466289-Doxorubicin,
pubmed-meshheading:9466289-Etoposide,
pubmed-meshheading:9466289-Female,
pubmed-meshheading:9466289-Hematopoietic Stem Cell Transplantation,
pubmed-meshheading:9466289-Humans,
pubmed-meshheading:9466289-Ifosfamide,
pubmed-meshheading:9466289-Immunosuppressive Agents,
pubmed-meshheading:9466289-Kidney Neoplasms,
pubmed-meshheading:9466289-Lung Neoplasms,
pubmed-meshheading:9466289-Salvage Therapy,
pubmed-meshheading:9466289-Vincristine,
pubmed-meshheading:9466289-Wilms Tumor
|
pubmed:year |
1997
|
pubmed:articleTitle |
Double high-dose chemotherapy with autologous peripheral stem cell rescue in relapsed Wilms' tumor.
|
pubmed:affiliation |
Department of Pediatrics, University Hospital Innsbruck, Austria.
|
pubmed:publicationType |
Journal Article,
Case Reports
|