Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-1-27
pubmed:abstractText
The paper deals with the formulation of a potential local anaesthetic--pentacaine into appropriate drug forms. To be more specific, the pentacaine is studies from the two aspects. First, the influence of auxiliary substances and their respective concentrations on the both onset and duration of local anaesthetic effects of pentacaine solutions. Second, the liberation of pentacaine from hydrogels and suppositories. Based on the obtained results, optimal auxiliary substances together with their optimal concentration are recommended.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Anesthetics, Local, http://linkedlifedata.com/resource/pubmed/chemical/Carbamates, http://linkedlifedata.com/resource/pubmed/chemical/Carboxymethylcellulose Sodium, http://linkedlifedata.com/resource/pubmed/chemical/Cellulose, http://linkedlifedata.com/resource/pubmed/chemical/Excipients, http://linkedlifedata.com/resource/pubmed/chemical/Gels, http://linkedlifedata.com/resource/pubmed/chemical/Glycerol, http://linkedlifedata.com/resource/pubmed/chemical/Lactose, http://linkedlifedata.com/resource/pubmed/chemical/MK 458, http://linkedlifedata.com/resource/pubmed/chemical/Methylcellulose, http://linkedlifedata.com/resource/pubmed/chemical/Ophthalmic Solutions, http://linkedlifedata.com/resource/pubmed/chemical/Oxazines, http://linkedlifedata.com/resource/pubmed/chemical/Plant Oils, http://linkedlifedata.com/resource/pubmed/chemical/Polymers, http://linkedlifedata.com/resource/pubmed/chemical/Propylene Glycols, http://linkedlifedata.com/resource/pubmed/chemical/Sorbitol, http://linkedlifedata.com/resource/pubmed/chemical/Suppositories, http://linkedlifedata.com/resource/pubmed/chemical/arachis oil, http://linkedlifedata.com/resource/pubmed/chemical/hydroxyethylcellulose, http://linkedlifedata.com/resource/pubmed/chemical/pentacaine, http://linkedlifedata.com/resource/pubmed/chemical/polypropylene glycol
pubmed:status
MEDLINE
pubmed:issn
0001-6837
pubmed:author
pubmed:issnType
Print
pubmed:volume
53
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
253-8
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed-meshheading:9415194-Anesthesia, pubmed-meshheading:9415194-Anesthetics, Local, pubmed-meshheading:9415194-Animals, pubmed-meshheading:9415194-Cacao, pubmed-meshheading:9415194-Carbamates, pubmed-meshheading:9415194-Carboxymethylcellulose Sodium, pubmed-meshheading:9415194-Cellulose, pubmed-meshheading:9415194-Chemistry, Pharmaceutical, pubmed-meshheading:9415194-Cricetinae, pubmed-meshheading:9415194-Excipients, pubmed-meshheading:9415194-Gels, pubmed-meshheading:9415194-Glycerol, pubmed-meshheading:9415194-Lactose, pubmed-meshheading:9415194-Methylcellulose, pubmed-meshheading:9415194-Ophthalmic Solutions, pubmed-meshheading:9415194-Oxazines, pubmed-meshheading:9415194-Plant Oils, pubmed-meshheading:9415194-Polymers, pubmed-meshheading:9415194-Propylene Glycols, pubmed-meshheading:9415194-Rabbits, pubmed-meshheading:9415194-Sorbitol, pubmed-meshheading:9415194-Suppositories
pubmed:articleTitle
Study of local anaesthetics. Part 136. Influence of auxiliary substances on the release of pentacaine from drug forms.
pubmed:affiliation
Department of Galenic Pharmacy, Faculty of Pharmacy, Comenius University, Bratislava, Slovak Republic.
pubmed:publicationType
Journal Article