rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1998-1-30
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pubmed:abstractText |
Amphetamine produces locomotor stereotypy (repetitive routes of locomotion) in an open field. In this research we tested the ability of the D1 antagonist SKF 83566 and the D2 antagonist sulpiride to block the locomotor stereotypy produced by 2 mg/kg amphetamine. SKF 83566 decreased amphetamine-induced locomotor stereotypy; sulpiride had no consistent effect on amphetamine-induced locomotor stereotypy. There was no evidence that either antagonist potentiated the effect of the other.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/2,3,4,5-Tetrahydro-7,8-dihydroxy-1-p...,
http://linkedlifedata.com/resource/pubmed/chemical/Amphetamine,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Antagonists,
http://linkedlifedata.com/resource/pubmed/chemical/Dopamine Uptake Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D1,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Dopamine D2,
http://linkedlifedata.com/resource/pubmed/chemical/SK&F 83566,
http://linkedlifedata.com/resource/pubmed/chemical/Sulpiride
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0091-3057
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
58
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1015-9
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9408208-2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine,
pubmed-meshheading:9408208-Amphetamine,
pubmed-meshheading:9408208-Animals,
pubmed-meshheading:9408208-Dopamine Antagonists,
pubmed-meshheading:9408208-Dopamine Uptake Inhibitors,
pubmed-meshheading:9408208-Drug Interactions,
pubmed-meshheading:9408208-Male,
pubmed-meshheading:9408208-Rats,
pubmed-meshheading:9408208-Rats, Wistar,
pubmed-meshheading:9408208-Receptors, Dopamine D1,
pubmed-meshheading:9408208-Receptors, Dopamine D2,
pubmed-meshheading:9408208-Stereotyped Behavior,
pubmed-meshheading:9408208-Sulpiride
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pubmed:year |
1997
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pubmed:articleTitle |
Amphetamine-induced locomotor stereotypy in rats is reduced by a D1 but not a D2 antagonist.
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pubmed:affiliation |
Department of Psychology, Texas Christian University, Fort Worth 76129, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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