Linked Life Data

9397347

Source:http://linkedlifedata.com/resource/pubmed/id/9397347

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1998-2-12
pubmed:databankReference
pubmed:abstractText
To further elucidate the cellular mechanisms that mediate programmed cell death in avian immune cells, differential display analysis was employed to identify differentially expressed genes in chicken thymocytes undergoing apoptosis. Primary cultures of thymocytes were treated with dexamethasone to activate apoptosis and RNA was isolated for differential display analysis. A differential display product designated A1 (479 bp) was identified. This display product was subcloned and induced expression of the genes was confirmed by ribonuclease protection analysis. Nucleotide sequence analysis of A1 revealed a putative 82 amino acid open reading frame that demonstrated limited homology with Bad, an apoptotic regulatory protein. Thus, A1 may represent the avian homolog of Bad.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0145-305X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
413-24
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Identification of a differential display product associated with apoptosis in chicken thymocytes.
pubmed:affiliation
Department of Poultry Science, University of Georgia, Athens 30602-2772, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't