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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1976-9-25
|
| pubmed:abstractText |
The short half-life positron emitter 13N, as labeled ammonia (13NH4+), was evaluated as a myocardial imaging agent. Regional myocardial uptake of 13NH4 correlated with the distribution of labeled microspheres in experimental myocardial infarction. Using intravenous 13NH4+, myocardial scintigraphy was performed in 85 cardiac patients and 27 normal subjects. Ninety-five scintigrams were suitable for analysis. Eighteen of 24 normal subjects had homogeneous myocardial images; six had inhomogeneous images attributable to early technical problems. Perfusion defects were observed in the scintigrams of 82% (57/65) of patients with coronary artery disease, being most common in patients with myocardial infarction (27/28). Six sequential studies showed changes in perfusion consistent with the clinical course of each patient. Scintigraphic abnormalities were also observed in 4/6 patients with valvular heart disease. 13NH4+ myocardial scintigraphy is a valid and sensitive method of assessing regional myocardial perfusion and is especially useful for sequential imaging at short intervals.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0009-7322
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
54
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
266-75
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:939024-Acute Disease,
pubmed-meshheading:939024-Adult,
pubmed-meshheading:939024-Aged,
pubmed-meshheading:939024-Ammonia,
pubmed-meshheading:939024-Angina Pectoris,
pubmed-meshheading:939024-Animals,
pubmed-meshheading:939024-Coronary Circulation,
pubmed-meshheading:939024-Diagnosis, Differential,
pubmed-meshheading:939024-Electrocardiography,
pubmed-meshheading:939024-Heart Valve Diseases,
pubmed-meshheading:939024-Humans,
pubmed-meshheading:939024-Liver,
pubmed-meshheading:939024-Lung,
pubmed-meshheading:939024-Metabolic Clearance Rate,
pubmed-meshheading:939024-Middle Aged,
pubmed-meshheading:939024-Myocardial Infarction,
pubmed-meshheading:939024-Myocardium,
pubmed-meshheading:939024-Nitrogen Radioisotopes,
pubmed-meshheading:939024-Radionuclide Imaging,
pubmed-meshheading:939024-Swine,
pubmed-meshheading:939024-Technetium
|
| pubmed:year |
1976
|
| pubmed:articleTitle |
Noninvasive evaluation of regional myocardial perfusion in 112 patients using a mobile scintillation camera and intravenous nitrogen-13 labeled ammonia.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
|