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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1998-1-15
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pubmed:abstractText |
The attachment of specific amino acids to the 3'-end of cognate transfer of RNAs (tRNAs) is catalyzed by a class of enzymes known as aminoacyl-tRNA synthetases (aaRS). We have previously demonstrated that Escherichia coli proline-tRNA synthetase (ProRS) can aminoacylate semi-synthetic tRNAs prepared by annealing two RNA oligonucleotides. We set out to examine the factors that are important in selective recognition of tRNAPro by ProRS, using semi-synthetic tRNAs and full-length tRNA transcripts.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1074-5521
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
661-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9383472-Amino Acids,
pubmed-meshheading:9383472-Amino Acyl-tRNA Synthetases,
pubmed-meshheading:9383472-Escherichia coli,
pubmed-meshheading:9383472-Mutagenesis, Site-Directed,
pubmed-meshheading:9383472-Nucleic Acid Conformation,
pubmed-meshheading:9383472-Plasmids,
pubmed-meshheading:9383472-RNA, Transfer, Pro,
pubmed-meshheading:9383472-RNA Probes,
pubmed-meshheading:9383472-Sequence Deletion,
pubmed-meshheading:9383472-Transcription, Genetic
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pubmed:year |
1995
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pubmed:articleTitle |
Use of semi-synthetic transfer RNAs to probe molecular recognition by Escherichia coli proline-tRNA synthetase.
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pubmed:affiliation |
Department of Chemistry, University of Minnesota, Minneapolis 55455, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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