Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-11-19
pubmed:abstractText
Pandemics of human immunodeficiency virus (HIV) type 1 infection and penicillin resistance highlight the urgency of preventing invasive pneumococcal disease with vaccination. We characterized pneumococcal serogroup distribution and the mortality rate among 460 patients with pneumococcal bacteremia from 1984 through 1994 at Denver General Hospital and the prevalence of HIV infection in patients for whom pneumococcal bacteremia was diagnosed from 1989 to 1994. Vaccine-related serogroups accounted for 426 isolates (92.6%), including 48 (92.3%) of 52 isolates from HIV-infected patients. Mortality among patients 15 years of age or older was higher during 1984-1988 (18[12.9%] of 140) than during 1989-1994 (10 [5.2%] of 191: rate ratio, 2.5; 95% confidence interval, 1.2-5.2). Of patients 15-59 years of age from 1989 to 1994, 44 (39.6%) of 111 men and three (7.3%) of 41 women were HIV-infected. Four (8.5%) of 47 HIV-infected patients and four (3.8%) of 105 other patients in this group died (age-weighted rate ratio, 1.8; 95% confidence interval, 0.5-6.2). We recommend routine screening of young adults with pneumococcal bacteremia for HIV infection and immunization of HIV-infected patients with pneumococcal vaccine (which includes most serogroups of infecting strains).
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1058-4838
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
195-9
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:9332509-AIDS-Related Opportunistic Infections, pubmed-meshheading:9332509-Adolescent, pubmed-meshheading:9332509-Adult, pubmed-meshheading:9332509-Aged, pubmed-meshheading:9332509-Antibodies, Bacterial, pubmed-meshheading:9332509-Antigens, Bacterial, pubmed-meshheading:9332509-Bacteremia, pubmed-meshheading:9332509-Child, pubmed-meshheading:9332509-Child, Preschool, pubmed-meshheading:9332509-Colorado, pubmed-meshheading:9332509-Female, pubmed-meshheading:9332509-HIV Infections, pubmed-meshheading:9332509-HIV-1, pubmed-meshheading:9332509-Humans, pubmed-meshheading:9332509-Infant, pubmed-meshheading:9332509-Infant, Newborn, pubmed-meshheading:9332509-Male, pubmed-meshheading:9332509-Middle Aged, pubmed-meshheading:9332509-Penicillin Resistance, pubmed-meshheading:9332509-Pneumococcal Infections, pubmed-meshheading:9332509-Prevalence, pubmed-meshheading:9332509-Streptococcus pneumoniae, pubmed-meshheading:9332509-Vaccination
pubmed:year
1997
pubmed:articleTitle
Prevalence of human immunodeficiency virus infection, mortality rate, and serogroup distribution among patients with pneumococcal bacteremia at Denver General Hospital, 1984-1994.
pubmed:affiliation
Infectious Disease Section, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S.