Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-4-6
pubmed:abstractText
Guidelines for the safe international movement of livestock embryos are provided in the International Animal Health Code of the Office International des Epizooties, and recommendations for embryo processing, based on numerous research papers on embryo-pathogen interaction studies, are given in the Manual of the International Embryo Transfer Society. Risk assessment is the logical extension of these approaches, since it provides veterinary authorities with a complete package of information on which to base their import/export decisions. Risk assessment includes evaluation of disease prevalence, effectiveness of Veterinary Services and competence of the embryo collection team. It also takes account of the epidemiology and pathogenesis of the disease concerned. The application of risk assessment for embryo movement is illustrated in this paper by comparisons of the probabilities of transmitting foot and mouth disease, bluetongue and vesicular stomatitis by bovine embryos. The risk scenario pathway was divided into three phases for analysis. The first phase deals with the potential for embryo contamination, which depends on the disease situation in the exporting region, the health status of donor herds and donor cows, and on the pathogenetic properties of the disease agent. The second phase covers risk mitigation by use of the internationally accepted standards for embryo processing, and the third phase considers the risk reductions resulting from post-collection surveillance of donors and donor herds, and also from testing of embryo-collection (flushing) fluids for the disease agent. It was evident from this assessment that low risks of transmitting disease by international movement of bovine embryos depend initially on a low disease incidence in the exporting region and on easily recognisable disease signs. Competent embryo processing was also of great importance, and in the case of bluetongue, vector ecology had a major influence. In addition to providing a logical basis for import/export decisions, risk assessment is useful for evaluating the potential outcome of new research and for assessing the safety of the movement of embryos of other species for which little or no research information is available on embryo-pathogen interactions.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0253-1933
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
226-39
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
The risks of disease transmission by embryo transfer in cattle.
pubmed:affiliation
Pan American Foot and Mouth Disease Center, Rio de Janeiro, Brazil.
pubmed:publicationType
Journal Article, Review