rdf:type |
|
lifeskim:mentions |
umls-concept:C0001471,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0086597,
umls-concept:C0439849,
umls-concept:C0445223,
umls-concept:C0445254,
umls-concept:C0521329,
umls-concept:C1521797,
umls-concept:C1533716,
umls-concept:C1552599,
umls-concept:C1704787,
umls-concept:C1880022
|
pubmed:issue |
3
|
pubmed:dateCreated |
1997-10-16
|
pubmed:abstractText |
Adenosine analogs have been shown to produce antinociception after intrathecal administration. To determine the adenosine receptor subtype involved in spinal antinociception, the effects of selective agonists and an antagonist on the evoked potentials recorded from a neonatal rat spinal cord were studied. The measured potentials are a slow ventral root potential (slow VRP), which is the C-fiber-evoked excitatory response associated with nociceptive information; a monosynaptic reflex (MSR), which reflects a non-nociceptive transmission related to motor function; and a dorsal root potential (DRP), which reflects a gamma-aminobutyric acidA (GABA(A)) receptor-mediated presynaptic inhibition associated with analgesia.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Sep
|
pubmed:issn |
0003-3022
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
87
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
577-84
|
pubmed:dateRevised |
2003-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9316963-Adenosine,
pubmed-meshheading:9316963-Adenosine-5'-(N-ethylcarboxamide),
pubmed-meshheading:9316963-Analgesics,
pubmed-meshheading:9316963-Animals,
pubmed-meshheading:9316963-Dose-Response Relationship, Drug,
pubmed-meshheading:9316963-Female,
pubmed-meshheading:9316963-Male,
pubmed-meshheading:9316963-Pain,
pubmed-meshheading:9316963-Rats,
pubmed-meshheading:9316963-Rats, Wistar,
pubmed-meshheading:9316963-Receptors, Purinergic P1,
pubmed-meshheading:9316963-Reflex, Monosynaptic,
pubmed-meshheading:9316963-Spinal Cord,
pubmed-meshheading:9316963-Theophylline
|
pubmed:year |
1997
|
pubmed:articleTitle |
Characterization of adenosine receptors mediating spinal sensory transmission related to nociceptive information in the rat.
|
pubmed:affiliation |
Department of Anesthesiology and Intensive Care, Hokkaido University School of Medicine, Sapporo, Japan.
|
pubmed:publicationType |
Journal Article
|