Linked Life Data

9309930

Source:http://linkedlifedata.com/resource/pubmed/id/9309930

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-11-19
pubmed:abstractText
The vaccination program for pertussis (whooping cough) in the United States consists of giving multiple doses of pertussis vaccine to young children. A demographic model with a steady-state age distribution is used as a basis for building an epidemiologic model for the transmission of pertussis. This age-structured model includes vaccination of infants and children for pertussis with waning of both infection-acquired and vaccine-induced immunity. Computer simulations of the mathematical model between 1940 and 2040 show the changes that took place during the implementation phase of the U.S. program and predict only minor future changes in the age distribution and incidence of pertussis if the vaccination program is maintained at the 1995 level. The sensitivities of these results to changes in demographic and epidemiologic parameters, vaccine efficacy, duration of protection, and levels of vaccination coverage are investigated.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0025-5564
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
145
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-136
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
An age-structured model for pertussis transmission.
pubmed:affiliation
Department of Mathematics, University of Iowa, Iowa City 52242, USA.
pubmed:publicationType
Journal Article, Historical Article