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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1997-12-17
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pubmed:abstractText |
The mechanism for the development of vitamin D deficiency in patients with malabsorption remains unclear. We wished to examine the hypothesis that one factor was a reduced skin content of 7-dehydrocholesterol, the precursor for the formation of vitamin D in the presence of ultraviolet radiation. We measured 7-dehydrocholesterol in skin samples from 9 patients who had previously had vitamin D deficiency due to malabsorption (6 with Crohn's disease, 2 with primary biliary cirrhosis, and 1 with idiopathic pseudo-obstruction). We found no evidence of reduced levels of 7-dehydrocholesterol in the skin in these patients. Lack of 7-dehydrocholesterol does not contribute to vitamin D deficiency in malabsorption.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0899-9007
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
771-3
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9290088-Adult,
pubmed-meshheading:9290088-Aged,
pubmed-meshheading:9290088-Cholesterol,
pubmed-meshheading:9290088-Chromatography, High Pressure Liquid,
pubmed-meshheading:9290088-Crohn Disease,
pubmed-meshheading:9290088-Dehydrocholesterols,
pubmed-meshheading:9290088-Female,
pubmed-meshheading:9290088-Humans,
pubmed-meshheading:9290088-Liver Cirrhosis, Biliary,
pubmed-meshheading:9290088-Malabsorption Syndromes,
pubmed-meshheading:9290088-Male,
pubmed-meshheading:9290088-Middle Aged,
pubmed-meshheading:9290088-Reproducibility of Results,
pubmed-meshheading:9290088-Skin,
pubmed-meshheading:9290088-Vitamin D,
pubmed-meshheading:9290088-Vitamin D Deficiency
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pubmed:year |
1997
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pubmed:articleTitle |
Skin content of 7-dehydrocholesterol in patients with malabsorption.
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pubmed:affiliation |
Department of Medicine, Ninewells Hospital and Medical School, Dundee, Scotland.
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pubmed:publicationType |
Journal Article
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