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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1997-10-20
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pubmed:abstractText |
During performance of a sequential finger opposition task we measured changes in regional cerebral blood oxygenation (rCBO) over the motor cortex and blood flow velocity changes (CBFV) in the middle cerebral artery in a combined near-infrared spectroscopy (NIRS) and transcranial Doppler Sonography (TCD) study. Stimulus duration was 60 followed by a 90 s rest period. During performance of the motor task we observed an increase in [oxy-Hb] a decrease in [deoxy-Hb] and an increase in MCA flow velocity. These changes were significantly more pronounced contralaterally than ipsilaterally to the moving hand. The time course of changes in [oxy-Hb] and CBFV were strikingly similar, showing a pronounced initial over-shoot. This study proves the feasibility of a simultaneous assessment of microcirculatory hemodynamics and cerebral oxygenation at high temporal resolution.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0065-2598
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
411
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
461-9
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9269463-Adult,
pubmed-meshheading:9269463-Blood Flow Velocity,
pubmed-meshheading:9269463-Brain,
pubmed-meshheading:9269463-Cerebrovascular Circulation,
pubmed-meshheading:9269463-Evaluation Studies as Topic,
pubmed-meshheading:9269463-Female,
pubmed-meshheading:9269463-Humans,
pubmed-meshheading:9269463-Male,
pubmed-meshheading:9269463-Microcirculation,
pubmed-meshheading:9269463-Middle Aged,
pubmed-meshheading:9269463-Motor Activity,
pubmed-meshheading:9269463-Motor Cortex,
pubmed-meshheading:9269463-Oxygen,
pubmed-meshheading:9269463-Spectroscopy, Near-Infrared,
pubmed-meshheading:9269463-Ultrasonography, Doppler, Transcranial
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pubmed:year |
1997
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pubmed:articleTitle |
Simultaneous assessment of cerebral oxygenation and hemodynamics during a motor task. A combined near infrared and transcranial Doppler sonography study.
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pubmed:affiliation |
Department of Neurology, Charité Humboldt-University Berlin.
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pubmed:publicationType |
Journal Article,
Comparative Study
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