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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
8
|
| pubmed:dateCreated |
1997-9-2
|
| pubmed:abstractText |
Alendronate and pamidronate are primary amino-bisphosphonates used in the treatment of metabolic bone disease. Both drugs have been associated with reversible erosive esophagitis and as a result pamidronate is approved in the United States only for parenteral use. In rats, alendronate causes acute gastric mucosal damage similar to that seen with aspirin or nonsteroidal anti-inflammatory drugs.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
0002-9270
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
92
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1322-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9260798-Adult,
pubmed-meshheading:9260798-Alendronate,
pubmed-meshheading:9260798-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:9260798-Aspirin,
pubmed-meshheading:9260798-Double-Blind Method,
pubmed-meshheading:9260798-Esophagus,
pubmed-meshheading:9260798-Female,
pubmed-meshheading:9260798-Gastric Mucosa,
pubmed-meshheading:9260798-Gastroscopy,
pubmed-meshheading:9260798-Humans,
pubmed-meshheading:9260798-Male,
pubmed-meshheading:9260798-Middle Aged,
pubmed-meshheading:9260798-Stomach Ulcer
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Primary amino-bisphosphonates: a new class of gastrotoxic drugs--comparison of alendronate and aspirin.
|
| pubmed:affiliation |
Department of Medicine, Veterans Affairs Medical Center, and Baylor College of Medicine, Houston, Texas 77030, USA.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, U.S. Gov't, Non-P.H.S.,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
|