Linked Life Data

9259956

Source:http://linkedlifedata.com/resource/pubmed/id/9259956

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-9-18
pubmed:abstractText
In two prenatal cases, de novo nonmosaic bisatellited marker chromosomes were studied with the combined use of fluorescence in situ hybridization (FISH) with chromosome specific probes and cytogenetic heteromorphisms. The FISH studies showed that one of the small accessory chromosome could be a heterozygous 14/15 or 15/22 translocation involving the p arms of these chromosomes, the other showed only one hybridization spot with the classical satellite probe of chromosome 15. The analysis of heteromorphisms of the parental acrocentric chromosomes demonstrated that the two markers were Robertsonian translocations involving in the first case the p arms of the maternal 15 and 22 chromosomes and in the second case the p arms of the maternal 14 and 15 chromosomes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0003-3995
pubmed:author
pubmed:issnType
Print
pubmed:volume
40
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
99-103
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Combined use of cytogenetic analysis and FISH for the identification of two antenatal de novo markers as Robertsonian translocations involving the p arms.
pubmed:affiliation
Center of Human Genetics, Galliera Hospital, Genova, Italy.
pubmed:publicationType
Journal Article, Case Reports